Repeated failures during in-vitro fertilization can pose a huge burden for a couple trying to conceive. Even though the couple has undergone a series of tests and from a genetic perspective there is nothing preventing the embryo transfer, the implantation of the embryo might repeatedly fail. The problem might be caused by the uterine lining, which might not be sufficiently prepared for the transfer.
The endometrium plays a crucial role
The endometrium, also known as the uterine lining, is located in the innermost part of the uterine wall. It is therefore a key factor for successful conception. The period of the menstrual cycle when the endometrium is in the optimal state for attachment and implantation of the embryo is called the implantation window. This brief period typically occurs around the 19th to 21st day of a regular menstrual cycle. In cycles with hormonal treatment, the endometrium is ready for implantation five days after the first dose of progesterone.
However, the growth of the lining is individual, both in natural and hormonally controlled cycles. It can be influenced by the physiological properties of the lining and its sensitivity to drugs. Up to 35% of women may have this implantation window shifted.
What is the beREADY test and who is it intended for?
Based on an analysis of a uterine swab sample, the beREADY test determines your individual implantation window, thus establishing the optimal time for embryo transfer. The test is intended for all women who, during treatment with assisted reproduction methods, have obtained a small number of embryos or have experienced repeated failures in embryo implantation. Test results are available within 14 working days. Therefore, the embryo transfer can be performed without delay in the subsequent cycle.
What is the difference between the beREADY test and the EndomeTRIO test?
EndomeTRIO is a complex examination that conducts three tests simultaneously from a single sample of the endometrial lining. In addition to determining the implantation window, it also analyzes the bacterial balance of the endometrium and detects bacteria causing chronic inflammation. On the other hand, the beREADY test only determines the implantation window, making it potentially more affordable.