PGT: Pre-implantation genetic screening

PGT: Preimplantation genetic screening

It helps prevent the potential transmission of disease from the parents to the baby. It allows for the diagnosis and selection of a healthy embryo before its implantation in the uterus. We perform PGT for the longest duration among all assisted reproduction centers in the Czech Republic. Thirty other IVF clinics also rely on us.

PGT: Preimplantation genetic screening

It helps prevent the potential transmission of disease from the parents to the baby. It allows for the diagnosis and selection of a healthy embryo before its implantation in the uterus. We perform PGT for the longest duration among all assisted reproduction centers in the Czech Republic. Thirty other IVF clinics also rely on us.

PGT-M: monogenic diseases

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Preimplantation genetic testing for monogenic diseases (PGT-M) is a method that allows for the selection of a healthy embryo without a specific genetic burden.

For whom the method is suitable

For all couples with a genetic burden in the family who are planning a baby

Approximate price

You can find out the current terms for the reimbursement of preimplantation examinations by consulting your doctor. For more detailed information about prices, see our price list.

How it works

We take a few cells from the embryos on the 5th to 6th days of their development. We then freeze the embryos and work only with those harvested cells. We perform Karyomapping or OneGene PGT tests in our genetic laboratory. We are able to rule out virtually any rare hereditary disease.

Genetic testing of embryos takes about 3 weeks. At the end, we get information about the genetic make-up of the embryos we have tested, so we know for sure which are suitable for transfer. The transfer can take place in the next cycle.

Schedule a non-binding consultation with us

And take the first step on your baby journey. The doctor will discuss with you everything you are interested in and suggest the next steps.

PGT-A: aneuploidy

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This method enables us to detect aneuploidy, i.e. changes in the embryo chromosome count. This allows us to select an embryo with a normal number of chromosomes, i.e. one that has the highest chance of successful nesting and healthy development. PGT-A thus reduces the number of cycles needed to get pregnant and give birth to a healthy baby.

For whom the method is suitable

  • For couples of higher reproductive age
  • For couples who have suffered repeated miscarriages or with experience of giving birth to a child with a developmental defect
  • For couples who have undergone cancer treatment
  • For couples with poor spermiogram parameters

Approximate price

You can find out the current terms for the reimbursement of preimplantation examinations by consulting your doctor. For more detailed information about prices, see our price list.

How it works

We take a few cells from the embryos on the 5th to 6th days of their development in the lab. We then freeze the embryos and continue working only with those harvested cells. They then undergo Massively Parallel Sequencing (MPS) testing in our genetics laboratory.

Genetic testing of embryos takes about 3 weeks. At the end, we get information about the genetic make-up of the embryos we have tested, so we know for sure which are suitable for transfer. The transfer can take place in the next cycle.

Schedule a non-binding consultation with us

And take the first step on your baby journey. The doctor will discuss with you everything you are interested in and suggest the next steps.

PGT-SR: structural chromosomal defects

This method allows us to detect chromosomal abnormalities in the embryo. This method is intended for couples where one or both partners are proven to carry a balanced translocation or other structural chromosomal rearrangement. Translocations are the most common structural abnormalities in chromosomes.

For whom the method is suitable

For couples where one or both partners are proven to carry a balanced translocation – i.e. signs of developmental defects are not manifested in the partners themselves, but the problem may arise when they decide to start a family.

Approximate price

You can find out the current terms for the reimbursement of preimplantation examinations by consulting your doctor. For more detailed information about prices, see our price list.

How it works

We take a few cells from the embryos on the 5th to 6th days of their development in the lab. We then freeze the embryos and continue working only with those harvested cells. They then undergo Massively Parallel Sequencing (MPS) testing in our genetics laboratory.

Genetic testing of embryos in the laboratory takes about 3 weeks. At the end we get information about whether some parts of the chromosome are present in higher numbers or are missing. Embryos unencumbered by a chromosomal translocation or other rearrangement are selected for transfer to the uterus and can be transferred in the next cycle.

Schedule a non-binding consultation with us

And take the first step on your baby journey. The doctor will discuss with you everything you are interested in and suggest the next steps.

Most frequently asked question

PGT-M can be used to rule out virtually any rare inherited disease (recessively hereditary, dominantly hereditary, even sex-linked). The most common rare diseases here are:

  • cystic fibrosis,
  • spinal muscular atrophy,
  • metabolic disorders,
  • neurofibromatosis,
  • Marfan syndrome,
  • Huntington’s chorea,
  • familial hypercholesterolemia,
  • Fragile X syndrome,
  • muscular dystrophy syndrome,
  • hereditary breast and ovarian cancers (BRCA1 and BRCA2).

Unfortunately, partners most often learn about the genetic burden only after the birth of a sick child. However, there are ways to avoid this occurring or to find out your genetic predispositions in advance.

You can test your genes and disposition for hereditary diseases at Repromeda using PANDA predictive genetic testing.

No, it isn’t. PGT significantly helps the birth of babies free of genetic burdens and the success rate of transfers continues to grow. In indicated cases, PGT is also paid for by the insurance company.

Biopsy of the embryo will not affect the future baby in any way. Here are three reasons why you have nothing to worry about.

  1. Biopsy is performed from the trophectoderm. This is the part of the embryo from which the fetal membranes subsequently emerge, not the fetus itself.
  2. During the biopsy, a very small number of cells are taken. Moreover, when they are taken, the embryo is at a stage when the cells are multiplying very rapidly.
  3. The biopsy is performed by our top embryologists, who themselves train embryologists around the world and have the highest possible qualifications.

For reliable PGT results we biopsy embryos on the 5th to 6th day of development. However, the appropriate time for transfer to the uterus is also 5th to 6th day of development, and it is not possible to perform genetic testing and transfer at the same time. Here at Repromeda we rely on cryoembryo transfer, which allows us to genetically examine the embryo and at the same time yields convincing results.

Unfortunately not. PGT requires cells collected from embryos. We cannot get the sample we need in the case of spontaneous conception. If pregnancy is already underway, prenatal testing is the only option. In this case, however, it is necessary to take into account the possible decision to terminate the pregnancy due to a genetic defect or the risk of giving birth to an affected child.

None. PGD, or Preimplantation Genetic Diagnosis, is an older – no longer used – term for PGT, or Preimplantation Genetic Testing.

PGT-M can be used to rule out virtually any rare inherited disease (recessively hereditary, dominantly hereditary, even sex-linked). The most common rare diseases here are:

  • cystic fibrosis,
  • spinal muscular atrophy,
  • metabolic disorders,
  • neurofibromatosis,
  • Marfan syndrome,
  • Huntington’s chorea,
  • familial hypercholesterolemia,
  • Fragile X syndrome,
  • muscular dystrophy syndrome,
  • hereditary breast and ovarian cancers (BRCA1 and BRCA2).

Unfortunately, partners most often learn about the genetic burden only after the birth of a sick child. However, there are ways to avoid this occurring or to find out your genetic predispositions in advance.

You can test your genes and disposition for hereditary diseases at Repromeda using PANDA predictive genetic testing.

No, it isn’t. PGT significantly helps the birth of babies free of genetic burdens and the success rate of transfers continues to grow.

Biopsy of the embryo will not affect the future baby in any way. Here are three reasons why you have nothing to worry about.

  1. Biopsy is performed from the trophectoderm. This is the part of the embryo from which the fetal membranes subsequently emerge, not the fetus itself.
  2. During the biopsy, a very small number of cells are taken. Moreover, when they are taken, the embryo is at a stage when the cells are multiplying very rapidly.
  3. The biopsy is performed by our top embryologists, who themselves train embryologists around the world and have the highest possible qualifications.

For reliable PGT results we biopsy embryos on the 5th to 6th day of development. However, the appropriate time for transfer to the uterus is also 5th to 6th day of development, and it is not possible to perform genetic testing and transfer at the same time. Here at Repromeda we rely on cryoembryo transfer, which allows us to genetically examine the embryo and at the same time yields convincing results.

Unfortunately not. PGT requires cells collected from embryos. We cannot get the sample we need in the case of spontaneous conception. If pregnancy is already underway, prenatal testing is the only option. In this case, however, it is necessary to take into account the possible decision to terminate the pregnancy due to a genetic defect or the risk of giving birth to an affected child.

None. PGD, or Preimplantation Genetic Diagnosis, is an older – no longer used – term for PGT, or Preimplantation Genetic Testing.

An unexpected connection of science, holistic medicine, and empathy

We seek the right connections to lead you to your desired goal.

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years

we’ve been here for you

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children

have been born thanks to us

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families

with a rare disease that we’ve helped

We are here for those who want more than just hope

We draw from our extensive experience and understand that each story is unique and deserves understanding and an individual approach.

Brno

RNDr. Gabriela Tauwinklová

R&D director

gtauwinklova@repromeda.cz

Brno

Mgr. Martina Pešáková

Head of the Embryology Laboratory

mpesakova@repromeda.cz

Brno

Mgr. David Kubíček, Ph.D.

Director of the Genetics Laboratory

dkubicek@repromeda.cz

Brno

Mgr. Miroslav Horňák, Ph.D.

R&D director

mhornak@repromeda.cz

Brno

Mgr. Rostislav Navrátil, Ph.D.

Head of Molecular Genetics Laboratory

rnavratil@repromeda.cz

Brno

MVDr. Vlasta Linková

Head of Cytogenetics Laboratory

vlinkova@repromeda.cz

We have already helped bring 6 000 children into the world

Amálka

March 19, 2024

Děkujeme za naši Amálku, která se narodila 4. 2. 2024. Moc děkujeme za splněný sen a přejeme nadále moc úspěchů.

Petr

January 31, 2024

The journey to our baby was long and difficult, but the wait was worth it. On 28th January at 5:45 in the morning our little happiness named Péťa was born, weighing 3 770 g.

Anička

January 24, 2024

Thank you to the whole team for our little Anička. Thanks to your support, we’ve had a great, easy-going girl at home since December 6, 2023.

Schedule a non-binding consultation with us

And take the first step on your baby journey. The doctor will discuss with you everything you are interested in and suggest the next steps.

Brno, Studentská 812/6

Your questions will be answered Mon-Fri, 7am-6pm.

Emergency +420 602 592 842
Ostrava, Dr. Slabihoudka 6232/11

Your questions will be answered Mon-Fri, 7am-3pm.

Emergency +420 606 029 983
Brno, Studentská 812/6

Your questions will be answered Mon-Fri, 7am-6pm.

Emergency +420 602 592 842

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Ostrava, Dr. Slabihoudka 6232/11

Your questions will be answered Mon-Fri, 7am-3pm.

Emergency +420 606 029 983

View on map

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