MOON is an advanced microscopic method for the detailed examination of the maturity of oocytes (eggs). Evaluating the maturity of oocytes using this technique is non-invasive and has no adverse impact on living cells.
During this examination, the embryologist examines the eggs under a microscope using polarized light. This allows them to see the spindle inside the egg, which is not visible under a regular light microscope. The spindle is an organelle that controls cell division and determines whether and at what time the egg is capable of accepting sperm and initiating embryo formation and development.
The aim is to determine the most suitable moment for micromanipulative fertilization of eggs with sperm (ICSI), that is, the moment when there is the highest probability of successful embryo formation.
For whom is the method suitable?
The method is especially useful for women from whom a low overall number of oocytes (5 or fewer) are retrieved or for those with a low number of mature oocytes. Additionally, we recommend this method for women of advanced reproductive age (over 40 years), as oocyte maturation typically progresses more slowly in this group.