What is the PICSI method?
This is a modification of the ICSI method associated with the selection of the optimal sperm. The principle of the method is the binding of mature sperm to a specially treated surface of a Petri dish, which is coated with a hyaluronan gel.
What is the principle of the method?
Hyaluronan is an essential natural component of the egg’s outer layers, and the head of a mature sperm carries a specific receptor that allows it to bind to hyaluronan. With the PICSI method, the embryologist selects those sperm that demonstrate positive binding to the gel with hyaluronan for micro-manipulative fertilization.
Why choose PICSI?
Using PICSI, one can select optimally mature sperm for egg fertilization. It is presumed that mature sperm, once introduced into the egg’s cytoplasm, has a higher likelihood of leading to fertilization and the development of a promising embryo.
Our clinic’s recommendations
If in previous cycles the proportion of fertilized eggs was low, embryos did not develop optimally, or there was a miscarriage, choose the PICSI method for fertilization. PICSI utilizes the principles and benefits of natural fertilization, where only a mature sperm fertilizes the egg, and the ICSI method, where the sperm is directly injected into the egg’s cytoplasm.
