IVF treatment using donated eggs

IVF using donated eggs gives hope for a baby to women who cannot get pregnant with their own eggs.

IVF treatment using donated eggs

IVF using donated eggs gives hope for a baby to women who cannot get pregnant with their own eggs.

You're only 2 visits away from having a baby.

See how IVF treatment works

IVF success rate

During 4 IVF cycles 99% of couples get pregnant at our clinic.
Approximately 7 out of 10 couples need just one IVF cycle to get pregnant.

However, the success rate of IVF using donated reproductive cells is very individual and depends on many factors – your overall physical health, age, psychological state and the quality of your partner’s sperm.

Careful selection of donors

We select donors according to strict criteria. They undergo all the important examinations and we make sure that they and their families have no history of serious illnesses or psychiatric diagnoses.

Of course, genetic compatibility with the male partner, blood group compatibility and the physical similarity of the donor and recipient are also important.

One coordinator and years of experience

IVF treatment with donated reproductive cells is one of the key programs we have focused on since founding Repromeda.

A team of experienced professionals will take care of you and one coordinator, whom you can contact at any time, will guide you through the entire treatment.

Quick start of treatment

We won’t keep you waiting for longer than necessary. We’re able to start your treatment promptly to help you on your way to your dream baby as quickly as possible. Call or email us to arrange a non-binding consultation.

Schedule a non-binding consultation with us

And take the first step on your baby journey. The doctor will discuss with you everything you are interested in and suggest the next steps.

How IVF treatment with donated eggs works

1. Initial consultation

The initial consultation is the gateway to IVF treatment and takes around 2 hours.

After making an appointment using the contact form, you will be contacted by our English-speaking coordinator who will discuss everything that interests you. You do not need to choose your appointment date according to your menstrual cycle, but can come at any time. You do not need to bring any other test results along with you to the appointment.

We recommend that you both come to the consultation.

More about the initial consultation

The examination of male fertility is based on the spermiogram, i.e. the analysis of ejaculate. Based on the results of the spermogram, we will suggest further treatment and genetic tests.

More about the examination

Reproductive cell donation is strictly anonymous in the Czech Republic. Donors and recipients cannot identify each other. We select a suitable donor for you based on blood type and Rh factor. We also seek the closest possible match in terms of hair and eye colour, height or even personality traits and interests.

The entire OD cycle process from the consultation with the doctor to the embryo transfer takes approximately 4 months.

More about choosing donor

Sperm is retrieved by masturbating into a sterile container after two to three days of sexual abstinence.

You can go to the retrieval room alone or with your partner. Alternatively, you can bring the sample from your home or hotel by prior arrangement.

More about sperm retrieval and freezing

Egg fertilization

The embryologist evaluates the quality of the eggs and fertilizes each of them with one sperm. Fertilization is performed using active micromanipulation methods (ICSI, PISCI), which significantly increase the embryo formation success rate.

Cultivation

After fertilization, we monitor the embryos and make sure they develop properly. The embryo is cultured for 5 to 6 days to the blastocyst stage. The best embryo care is provided by the MIRI Time-Lapse Incubator.

More about egg fertilization and cultivation

Cryopreservation, or the freezing of embryos, allows embryos to be stored for future use.
Frozen embryos can be stored for several decades, after which they are thawed and then transferred to the uterus.
After a failed IVF process or if you wish to have another pregnancy, you do not have to undergo the egg and sperm retrieval process again.
We use a state-of-the-art technique called vitrification to freeze embryos.
During this process, the embryos are rapidly cooled to a final temperature of -196 °C within seconds.

More about cryopreservation

The embryo is transferred through a thin cannula through the cervix into the uterus.
The transfer is usually completely painless and you and your partner can enjoy this moment, which might result in a new life.

More about embryo transfer

After the transfer, enjoy some peace and comfort and take the medication recommended by your doctors. If you do not get your period within 14 days of the embryo transfer, you can take a pregnancy test at home.

We will contact you after 14 days to discuss the next steps.

More information

Schedule a non-binding consultation with us

And take the first step on your baby journey. The doctor will discuss with you everything you are interested in and suggest the next step.

Most frequently asked question

In order to undergo IVF, a woman needs the signature of her partner, who does not have to be her legal husband. At the same time, the woman is not obliged to name the man as the father of the child after the birth.

By law, a woman can undergo assisted reproduction methods up to the age of 49.

A consultation with our doctor is the first step to successful treatment. During the consultation, the doctor will discuss with you your family and personal history, the course of all the examinations you have already undergone, and the procedure for the examinations and treatment you have yet to undergo. The doctor will also inform you about prices and reimbursement options from your health insurance company. Both you and your partner should attend the consultation.

One third of cases involve the male infertility factor, the female factor plays a role in a third of cases, and the last third is due to the combined infertility factor.

Specifically, we can say that in men it is mostly a question of poor spermiogram parameters, especially a low number and poor motility or morphology (shape) of the man’s sperm.

Ovulation disorders (egg maturation and release), low egg quality, endometriosis, fallopian tube obstruction, ovarian and fallopian tube adhesions are often detected in women.

Both genetic partners may also have some genetic variations that will not allow the development of the embryo and lead to infertility or repeated miscarriages.

In order to undergo IVF, a woman needs the signature of her partner, who does not have to be her legal husband. At the same time, the woman is not obliged to name the man as the father of the child after the birth.

By law, a woman can undergo assisted reproduction methods up to the age of 49.

A consultation with our doctor is the first step to successful treatment. During the consultation, the doctor will discuss with you your family and personal history, the course of all the examinations you have already undergone, and the procedure for the examinations and treatment you have yet to undergo. The doctor will also inform you about prices and reimbursement options from your health insurance company. Both you and your partner should attend the consultation.

An unexpected connection of science, holistic medicine, and empathy

We seek the right connections to lead you to your desired goal.

0
years

we’ve been here for you

0
children

have been born thanks to us

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families

with a rare disease that we’ve helped

We are here for those who want more than just hope

We draw from our extensive experience and understand that each story is unique and deserves understanding and an individual approach.

Ostrava, Brno

Bc. Michaela Janíčková, DiS.

Head nurse

mjanickova@repromeda.cz

+420 702 247 322

Brno

Bc. Barbora Šobová

Day Coordinator

bsobova@repromeda.cz

+420 607 001 671

Brno

Dana Kochová

Day Coordinator

dkochova@repromeda.cz

+420 722 972 193

Brno

Bc. Martina Tocháčková, DiS.

Nurse

Brno

Adéla Klepetková, DiS.

Nurse

Brno

Eliška Široká

Nurse

Methods increasing IVF success

We offer several supportive methods that will most likely shorten your baby journey.

BeREADY

The test is intended for all women who, during treatment with assisted reproduction methods, have obtained a small number of embryos or experience repeated embryo implantation failures.

EndomeTRIO

An examination that includes three tests from one sample of the uterine lining. A detailed examination of the uterine environment and determining the optimal moment for embryo transfer can be a very important step in identifying the cause of infertility.

SpermMobil

A special medium used to artificially activate sperm. Adding the medium to a sample of completely immotile sperm activates the energy reserves of live sperm, which gain motility. This makes it easy to distinguish live sperm from dead sperm.

MACS

Sperm have a limited lifespan and undergo a process called apoptosis. Apoptotic sperm cannot be typically distinguished from normal sperm. To exclude damaged sperm from a semen sample, the MACS® ART Annexin V system is used.

Halosperm

Based on the sperm analysis, besides evaluating the count, volume, motility, and morphology of the sperm, we can also assess the degree of their DNA damage (fragmentation). We examine the DNA of the sperm using a specialized test called Halosperm G2.

Immasperm

Within the diagnosis of male infertility factors, an important parameter is, among other things, determining the proportion of immature sperm in the semen. Sperm maturity is determined by Immasperm (a diagnostic tool) based on the staining intensity of the sperm.

Examination of oxidative stress in the semen

Oxidative stress affects the quality and functionality of sperm and causes damage to their DNA. To detect oxidative stress, we use the fastest and most accurate test, MIOXSYS. This test enhances the accuracy of male infertility diagnosis.

Time-lapse

The MIRI TL incubator offers embryos the best care, comfort, and individual space. The embryos of each couple are cultured separately in one of the 12 separete heated chambers.

EmbryoGlue

The transfer of an embryo into the uterus is one of the most crucial steps in IVF treatment. EmbryoGlue is a special culture medium containing hyaluronan that acts like "glue". During the transfer, it helps the embryo adhere to the uterine wall while also providing all the necessary nutrients.

We have already helped bring 6 000 children into the world

Amálka

March 19, 2024

Děkujeme za naši Amálku, která se narodila 4. 2. 2024. Moc děkujeme za splněný sen a přejeme nadále moc úspěchů.

Petr

January 31, 2024

The journey to our baby was long and difficult, but the wait was worth it. On 28th January at 5:45 in the morning our little happiness named Péťa was born, weighing 3 770 g.

Anička

January 24, 2024

Thank you to the whole team for our little Anička. Thanks to your support, we’ve had a great, easy-going girl at home since December 6, 2023.

Schedule a non-binding consultation with us

And take the first step on your baby journey. The doctor will discuss with you everything you are interested in and suggest the next steps.

Brno, Studentská 812/6

Your questions will be answered Mon-Fri, 7am-6pm.

Emergency +420 602 592 842
Ostrava, Dr. Slabihoudka 6232/11

Your questions will be answered Mon-Fri, 7am-3pm.

Emergency +420 606 029 983
Brno, Studentská 812/6

Your questions will be answered Mon-Fri, 7am-6pm.

Emergency +420 602 592 842

View on map

Ostrava, Dr. Slabihoudka 6232/11

Your questions will be answered Mon-Fri, 7am-3pm.

Emergency +420 606 029 983

View on map

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3. Choosing a suitable donor

Reproductive cell donation is strictly anonymous in the Czech Republic. Donors and recipients cannot identify each other. We select a suitable donor for you based on blood type and Rh factor. We also seek the closest possible match in terms of hair and eye colour, height or even personality traits and interests.

The entire OD cycle process from the consultation with the doctor to the embryo transfer takes approximately 4 months.

4. Sperm retrieval and freezing

Sperm is retrieved by masturbating into a sterile container after two to three days of sexual abstinence. Longer abstinence is not desirable as it may not give the expected result. For this purpose, the clinic has a special discreet room where you can go alone or accompanied by your partner. You can also bring a sample (in a container issued by the clinic) from your home or hotel. However, you must be able to do this within an hour and hand it in yourself.

We then freeze the sperm so that it is ready to use on the day we receive the eggs from the donor.

8. After the transfer

After the transfer, enjoy some peace and comfort and take the medication recommended by your doctors. In 14 days, take a pregnancy test from your morning urine. We will call you the same day, ask you about the test results, and we’ll agree on the next steps together.

Most frequently asked question

Why can’t I take a pregnancy test until 14 days after the transfer?
During the course of IVF treatment, you take a number of drugs that can skew the result towards either a false positive or a false negative. By taking the test after 14 days, you will save yourself the unnecessary stress that could arise from false results.

Yet another control line. What should I do now?
Unfortunately, sometimes things don’t go the way we imagine and good news doesn’t come the moment we long for it the most. Don’t worry, you’re not alone. Unfortunately, even IVF treatment is not 100% successful. The IVF success rate varies depending on various factors such as your age, health and mental state. Do what you feel is right. Scream, cry, be silent, talk about it. Give vent to all your feelings. But don’t blame yourself. If you’d like to talk to a psychologist or our staff about this, we’re happy to help.

It was my first IVF failure; should I change my treatment?
With the first or second IVF failure, nothing happens. You don’t have to change anything. But if you’re wondering what else you can do to make sure you get two lines on your pregnancy test next time, we have a few tips for you. Try the beREADY endometrial receptivity test to find out your exact implantation window and determine the ideal time for your next transfer. You can also try the EndomeTRIO test, which, like the beREADY test, determines the implantation window. In addition, however, it also analyses the balance of bacteria in the endometrium and detects bacteria causing chronic inflammation.

Try the beREADY endometrial receptivity test to find out your exact implantation window and determine the ideal time for your next transfer. You can also try the EndomeTRIO test, which, like the beREADY test, determines the implantation window. In addition, however, it also analyses the balance of bacteria in the endometrium and detects bacteria causing chronic inflammation.

Do you believe in a holistic approach? So do we. Alternative medicine may not be what will always guarantee motherhood. However, it is a suitable complement to the methods of Western medicine and can really improve your health significantly.

More about alternative methods

We’ve failed repeatedly, so what now?

Your doctor may offer you the option of treatment using donated reproductive cells. We know that this decision takes time and that you will need to think about it carefully. Take your time. Everything will come when the time is right.

6. Cryopreservation

Cryopreservation, or the freezing of embryos, allows embryos to be stored for future use.
Frozen embryos can be stored for several decades, after which they are thawed and then transferred to the uterus.

These embryos can be used after a failed transfer or if you are considering siblings in a few years.

The current cryopreservation technique used in all modern workplaces is vitrification. During this process, the embryos are rapidly cooled to a final temperature of -196 °C in a few seconds, at which the cells are then stored.

We were among the first in the Czech Republic to introduce an open vitrification system in 2020. Thanks to this technique, the thawing success rate after vitrification is significantly higher and we can benefit from all the advantages of cryoembryo transfer (CET).

Most frequently asked questions

Are thawed embryos really just as good as fresh ones? Don’t we have to worry about them being damaged somehow?
Unlike the slow freezing method previously used, vitrification does not produce any ice crystals that could damage the cells. In addition, the cells are stored in special media that protect them from external factors. Even after thawing, the embryos are in excellent condition.

7. Embryo transfer

Transferring the embryo into the uterus is one of the most important steps in IVF treatment. In simple terms, it can be described as the transfer of the embryo through a thin cannula through the cervix into the uterus. The procedure is short, usually painless and is performed in the transfer room against a backdrop of relaxing music. During the transfer, you can watch a video recording of the transfer of the selected embryo and your partner can also be present during the procedure.

Embryos are ideally introduced into the uterus at the blastocyst stage. This is the 5th-6th day after the eggs have been fertilized by sperm. One option is to perform a fresh transfer; the other option is to freeze these embryos and transfer them in the next cycle (cryoembryo transfer – CET). It is the second option that we prefer at Repromeda.

Acupuncture is a suitable complement before and after the transfer. Before the transfer, you will be pleasantly attuned and your pelvic area will be relaxed, making it easier to insert the embryo. After the transfer, acupuncture is used to stimulate the circulation of blood to the uterus, which promotes nutrition and facilitates the proper development of the embryo. In addition, you will find it nice and relaxing.

What if the embryo attachment repeatedly fails?

It may happen that, despite a series of tests showing that nothing is preventing the embryo from attaching, it repeatedly fails to attach. The problem may be caused by a uterine lining that may not be sufficiently prepared for the transfer. The beReady or EndomeTRIO test can help you with this.

  • Based on an analysis of a uterine swab sample, the beREADY test determines your individual implantation window and thus the optimal time for the transfer of the embryo.
  • The EndomeTRIO test performs three tests simultaneously from a single sample of the uterine mucosa. In addition to determining the implantation window, it also analyses the bacterial balance of the endometrium and detects bacteria causing chronic inflammation.
  • A special culture medium called EmbryoGlue can help increase the chances of embryo nesting and subsequent pregnancy. This medium is formulated to mimic the conditions in a woman’s uterus while acting as a “glue”. EmbryoGlue contains all the nutrients needed for optimal embryo development and facilitates attachment to the uterine wall during transfer.

Most frequently asked questions

Why do you prefer cryoembryo transfer or CET in Repromeda?
The main reason is the higher treatment success rate. Why is that? The timing of the transfer to the woman’s next natural cycle, which is no longer burdened by hormonal stimulation (necessary for egg retrieval), increases the success rate. In the following cycles, we are usually able to ensure that the uterine lining is better prepared to receive the embryo. Another reason is the use of preimplantation genetic testing of embryos, which we now perform on most of our patients. In this case, CET is the only option for time reasons. During the delayed transfer, we examine the embryos in our genetic laboratory. In the following cycle, we transfer the most promising embryos.

Is embryo transfer painful?
For most women, this is a painless outpatient procedure. In some women, the cervix may be narrowed because of a developmental defect of the uterus or as a result of inflammation or surgery. In this case, the transfer may be slightly uncomfortable.

Why do you transfer only one embryo during embryo transfer at Repromeda?
Because we know that transferring two or more embryos does not increase the likelihood of pregnancy; it only increases the likelihood of multiple pregnancy. By transferring one embryo, we prevent multiple pregnancies, which pose a risk to both the woman and the children. The final decision on the number of embryos to be transferred is made by the couple in consultation with their doctor. However, we are very happy that the average number of transferred embryos in our clinic is 1.0. Our goal is not only to get you pregnant, but also to see a healthy baby in your arms. This is the only way we ourselves can be satisfied with our work.

Can I have twins after a single embryo transfer?
With a single embryo transfer, multiple pregnancies can only occur in cases of identical twins resulting from the division of the original single transferred embryo.

How likely am I to get pregnant?
The probability of pregnancy after the transfer of one PGT-tested embryo is up to 58%. In most cycles, however, more viable embryos are obtained. Approximately 7 out of 10 couples only need one IVF cycle to achieve pregnancy. During 4 IVF cycles 99% of couples get pregnant.

5. Egg fertilization and cultivation

Fertilisation of eggs

Once we have the reproductive cells, we move to the embryology lab. This is where artificial insemination takes place. The embryologist assesses the quality of the eggs and then fertilizes each egg with one sperm. Fertilization is nowadays performed as standard using active micromanipulation methods (ICSI, PICSI), which significantly increase the embryo formation success rate.

We offer our clients a SpermPacket (for fertilization) containing a suitable combination of methods. This package includes ICSI or PICSI and optimal sperm selection, which is performed in two ways – MACS or a Zymot chip.

The method chosen to select the optimal sperm is based on previous laboratory tests, patient needs and current spermiogram parameters. The MACS method removes defective sperm with fragmented DNA from the ejaculate sample. The Zymot chip method gently sorts out the sperm with the highest motility and viability.

Embryo cultivation

After the egg has been fertilized with sperm, our embryologists monitor your embryos and make sure they develop properly. The embryo is cultured for 5 to 6 days to the blastocyst stage. We offer our clients the use of state-of-the-art MIRI Time-Lapse Incubators. These incubators ensure the best care for the embryos, providing a separate space for cultivation while continuously recording their development via a built-in camera. Since there is no need to remove them from the incubator for microscopic examination, there is no variation in the parameters of the culture conditions.

In cycles where preimplantation genetic testing (PGT), is planned, on the 5th – 6th day of development a few cells are taken from the embryo and this sample is tested in the genetic laboratory. Meanwhile, the embryos are vitrified (frozen).

Most frequently asked questions

What is classical or conventional IVF and why is it so rarely used these days?
This is a method in which eggs and sperm are placed in a “test tube” and we wait to see if spontaneous fertilization occurs without further intervention by an embryologist. However, this original method has a relatively low success rate and has been more or less replaced by the ICSI and PICSI methods.

What does the ICSI method involve?
The ICSI method is the most commonly used micromanipulation technique, in which embryologists actively transfer one sperm into each egg.

For whom is the PICSI method suitable and how exactly does it work?
The PICSI method is suitable for you if the proportion of eggs fertilized by ICSI has been low in previous cycles, if the embryos have not developed as well as they should or if there has been a miscarriage. The main role in the PICSI method is played by hyaluronan, which is an important natural component of the egg envelope. The head of a mature sperm carries a specific receptor that allows it to bind to hyaluronan. With the PICSI method, the embryologist selects for micromanipulation fertilization those sperm that show a positive binding to the hyaluronan gel.

2. Male examination

At Repromeda, we don’t believe in a one-size-fits-all approach. We believe that every couple is unique. Together, we will find the appropriate treatment for you with the least risk of complications and the greatest likelihood of success. However, to do this, we need to carry out several examinations at the outset.

What examinations are waiting for you?

  • Spermiogram
    The examination of male fertility is based on the spermiogram, i.e. the analysis of the ejaculate.In consultation with your doctor, you can choose the SpermPacket diagnostic package, which provides a comprehensive picture of male fertility. This includes:

    • spermiogram,
    • halosperm – determination of DNA fragmentation in sperm, i.e. the degree of DNA damage,
    • examination of oxidative stress in ejaculate – one of the tests assessing the reproductive capacity of sperm,
    • immasperm – determination of the percentage of mature sperm in the ejaculate.
  • Genetic testing
    Couples who have trouble conceiving often have structural chromosomal defects that can be detected by genetic testing. Determination of karyotype is a basic genetic examination that every couple undergoes at our clinic. However, we also offer more advanced genetic testing – PANDA Infertility and PANDA Carrier.
  • Immunological examination
    Some couples may have immunological causes of infertility, so this examination is also important and will help us determine the next course of action. If necessary, we will recommend further testing or a consultation with a reproductive immunologist.
  • Urological examination
    It is only performed in indicated cases when a man is found to have a more serious spermiogram disorder.

Frequently asked question

What does a spermiogram investigate?
The basic parameters of semen examination include determination of volume, pH, liquefaction, as well as determination of sperm count, motility and shape (morphology).

What can be the results of a spermiogram?
The examination can confirm or exclude sperm pathologies, but it cannot confirm that the man is actually fertile. Fertility is determined by the interaction between male and female fertility or infertility factors. Even if a man has a completely physiological spermogram, this does not exclude the possibility of other infertility factors – for example, gene mutations that may prevent fertilization of the egg.

Can I bring an ejaculate sample from home?
Yes, it is possible to bring a sample of ejaculate (in a labelled container issued by the clinic) from home. However, you must be able to do this within an hour of collection.

1. Initial consultation

The initial consultation is the gateway to the entire IVF treatment. During the course of 2 hours, your doctor will discuss your family and personal history and go over all the tests you have already had. Based on this information, we will suggest a course of action. You will also learn the approximate cost.

At the consultation you will have the opportunity to ask questions about anything you want, so we recommend that you come along with your partner. You don’t have to worry about us overwhelming you with specialist terms; the doctor will explain everything in a clear and comprehensible manner.

Your treatment will be guided at all times by a strategic doctor, who ill help you with anything you need and answer any questions you might have. However, other equally experienced doctors may also carry out certain lesser procedures. Our daily coordinators will also be available to guide you through your treatment.